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...Most signal transduction involves the binding of extracellular signaling molecules to cell-surface receptors. While triggering events inside the cell, such receptors typically face outward from the plasma membrane. Intracellular signaling cascades can also be triggered through cell-substratum interactions. One example is integrins, which bind ligands found within the extracellular matrix....
...Most signal transduction involves the binding of extracellular signaling molecules to cell-surface receptors. While triggering events inside the cell, such receptors typically face outward from the plasma membrane. Intracellular signaling cascades can also be triggered through cell-substratum interactions. One example is integrins, which bind ligands found within the extracellular matrix....
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